Formulation and Evaluation of Antibacterial Cream containing Dioscorea Bulbifera Linn

Abstract

The proposed study focuses on formulating and evaluating a topical antimicrobial cream using Dioscorea bulbifera (tuber) extracts. Ethanolic extract was incorporated into creams and evaluated for pH, spreadability, viscosity, and stability. Antimicrobial activity was tested using the agar well diffusion method against microbes from natural sources like nail dirt and acne pus, along with standard strains. The ethanolic extract-based cream showed stronger antimicrobial activity, especially against nail and acne bacterial cultured sample, indicating its greater potential for treating skin infections.